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	<title>Comments on: What is Complex Regional Pain Syndrome &#8211; in plain English</title>
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	<link>http://bodyinmind.com.au/what-is-complex-regional-pain-syndrome-in-plain-english/</link>
	<description>Research into the role of the brain and mind in chronic pain disorders</description>
	<lastBuildDate>Fri, 30 Jul 2010 02:42:09 +0000</lastBuildDate>
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		<title>By: Lorimer</title>
		<link>http://bodyinmind.com.au/what-is-complex-regional-pain-syndrome-in-plain-english/#comment-5786</link>
		<dc:creator>Lorimer</dc:creator>
		<pubDate>Wed, 28 Apr 2010 08:13:52 +0000</pubDate>
		<guid isPermaLink="false">http://www.bodyinmind.com.au/?p=2330#comment-5786</guid>
		<description>Hi Meg - thanks for this. CRPS is a diagnosis based on a group of signs (things you can see or detect) and symptoms (things the patient describes), not on a particular pathology. Most of us studying it would say it usually involves a limb, but there are no rules so to speak. Your really important question though, is what can be done for your daughter. This depends on many things, not least of which is where you are.  Perhaps if you let us know approximate location, we can try to link you up with someone. Best, Lorimer</description>
		<content:encoded><![CDATA[<p>Hi Meg &#8211; thanks for this. CRPS is a diagnosis based on a group of signs (things you can see or detect) and symptoms (things the patient describes), not on a particular pathology. Most of us studying it would say it usually involves a limb, but there are no rules so to speak. Your really important question though, is what can be done for your daughter. This depends on many things, not least of which is where you are.  Perhaps if you let us know approximate location, we can try to link you up with someone. Best, Lorimer</p>
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		<title>By: Meg Morgan</title>
		<link>http://bodyinmind.com.au/what-is-complex-regional-pain-syndrome-in-plain-english/#comment-5687</link>
		<dc:creator>Meg Morgan</dc:creator>
		<pubDate>Mon, 26 Apr 2010 07:35:59 +0000</pubDate>
		<guid isPermaLink="false">http://www.bodyinmind.com.au/?p=2330#comment-5687</guid>
		<description>Dear Lorimer
Does CRPS always involve a limb?
My 32yr old daughter has chronic neuopathic pain from a head injury sustained 4yrs ago, involving  fractured orbital and nasal bones. She is taking Gabapentin with some releif.
Can your research help her?
Where can she seek help?
Thankyou
(Mrs)  Meg Morgan</description>
		<content:encoded><![CDATA[<p>Dear Lorimer<br />
Does CRPS always involve a limb?<br />
My 32yr old daughter has chronic neuopathic pain from a head injury sustained 4yrs ago, involving  fractured orbital and nasal bones. She is taking Gabapentin with some releif.<br />
Can your research help her?<br />
Where can she seek help?<br />
Thankyou<br />
(Mrs)  Meg Morgan</p>
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		<title>By: Lorimer</title>
		<link>http://bodyinmind.com.au/what-is-complex-regional-pain-syndrome-in-plain-english/#comment-1630</link>
		<dc:creator>Lorimer</dc:creator>
		<pubDate>Mon, 11 Jan 2010 03:08:28 +0000</pubDate>
		<guid isPermaLink="false">http://www.bodyinmind.com.au/?p=2330#comment-1630</guid>
		<description>Hi Jenny - 
Thanks a million for taking the time to contribute!  It is great to hear of your successes relating to the management of CRPS.  I am not, obviously, very familiar with InterX, aside from our very brief conversations about it - there is clearly much to know!  I am, equally obviously, very keen to pursue better ways to treat people with CRPS and if InterX ends up being excellent than that would be excellent.  I guess, however, that we need the evidence.  This is not trivial because evidence is tricky to collect, but here is what i say to anyone who sees real successes in their clinical interactions: &quot;If it really is as good as you think it is, then we all should know about it. If it really isn&#039;t as good as you think it is, then you should know about it&quot;.  So, let&#039;s find out - I would be happy to help here if i can.  In the meantime, we rely on what evidence there is and the evidence we currently have for TENS as a way to treat CRPS, is not good - remembering CRPS is not &#039;just another chronic pain&#039;.  We can also utilise what we know about the mechanisms that underpin CRPS and here i am a little lost.  I don&#039;t know how it could work.  This reflects my ignorance perhaps, but i am, as i said, very keen to pursue the truth, wherever it may lie.  How do you reckon it would work in CRPS? Again, thanks for bothering to contribute - we appreciate it. Feel free to pose an answer to that one won&#039;t you?</description>
		<content:encoded><![CDATA[<p>Hi Jenny &#8211;<br />
Thanks a million for taking the time to contribute!  It is great to hear of your successes relating to the management of CRPS.  I am not, obviously, very familiar with InterX, aside from our very brief conversations about it &#8211; there is clearly much to know!  I am, equally obviously, very keen to pursue better ways to treat people with CRPS and if InterX ends up being excellent than that would be excellent.  I guess, however, that we need the evidence.  This is not trivial because evidence is tricky to collect, but here is what i say to anyone who sees real successes in their clinical interactions: &#8220;If it really is as good as you think it is, then we all should know about it. If it really isn&#8217;t as good as you think it is, then you should know about it&#8221;.  So, let&#8217;s find out &#8211; I would be happy to help here if i can.  In the meantime, we rely on what evidence there is and the evidence we currently have for TENS as a way to treat CRPS, is not good &#8211; remembering CRPS is not &#8216;just another chronic pain&#8217;.  We can also utilise what we know about the mechanisms that underpin CRPS and here i am a little lost.  I don&#8217;t know how it could work.  This reflects my ignorance perhaps, but i am, as i said, very keen to pursue the truth, wherever it may lie.  How do you reckon it would work in CRPS? Again, thanks for bothering to contribute &#8211; we appreciate it. Feel free to pose an answer to that one won&#8217;t you?</p>
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		<title>By: jenny crane</title>
		<link>http://bodyinmind.com.au/what-is-complex-regional-pain-syndrome-in-plain-english/#comment-1629</link>
		<dc:creator>jenny crane</dc:creator>
		<pubDate>Mon, 11 Jan 2010 02:06:18 +0000</pubDate>
		<guid isPermaLink="false">http://www.bodyinmind.com.au/?p=2330#comment-1629</guid>
		<description>Hi Lorimer
After reading your blog and comment re TENS and CRPS I wanted to respond as I have seen TENS like stimulation be affective when incorporated into the overall management plan for people with CRPS. Our company distributes the Interx device which we often descrive as &quot;TENS&quot; like, even though the application is very different.
It may well be considered that TENS is not indicated for the treatment of pain relating to the condition CRPS due the lack of long term benefit or inconsistency of results that are commonly experienced. However, it may be necessary to look further into the way the technology is applied to determine whether or not it has a place in the treatment of such difficult conditions. TENS is a broad category which incorporates many different technologies applied in a variety of ways . The way a modality is used can have a significant affect on the outcomes achieved.

Recent analysis of the effect that treatment parameters of TENS have on pain relief clearly demonstrates that it is possible to optimize those parameters to achieve more pain relief.   The importance of treatment amplitude, pulse frequency and treatment location  have all been shown in recent literature and even in articles dated as far back as 1975 (Melzack et al)  .

Based upon my experience of the benefit of InterX therapy and the successful treatment of very difficult conditions including CRPS, Allodynia, Phantom Pain and others , I suggest that the technology of TENS which has barely evolved in the last 30 yrs limits the ability of a therapist to optimize treatment parameters for the effective relief of pain from CRPS. The protocols used with InterX dictate both an extra segmental and segmental approach for the treatment of CRPS. This includes contralateral treatment, treatment of the whole spine and the face and scalp. The crucial technological aspect of InterX is that it allows the identification of optimal treatment points within  chosen treatment areas while also delivering a significant dose of stimulation (typically 45mA). The identification of treatment points is based upon patients’ physiological response (increased sympathetic skin response) ,  and not arbitrary or anatomical points. The dose is an important factor and the InterX amplitude is approximately three times higher than Bjordal et al considered high amplitude and thus important for the success of a treatment.

If this scientific application of a modality excludes InterX from the classification of TENS then so be it, but it does not fall into the category of electroacupuncture either as points of low impedance are not always acupuncture points. As such InterX (Interactive Neurostimulation) may be considered in any of the above categories or in one of its own as a scientific delivery of high amplitude stimulation to points relating to a patients sympathetic nerve activity. Either way, it should be noted that even if  “TENS” is not indicated for the treatment of CRPS, it does not mean that TENS-like technologies when scientifically and correctly applied cannot offer sufferers of CRPS significant relief of their pain. This relief can bring them back into functional rehabilitation and ultimately to achieve long term relief with the aid of an integrated approach. With spinal cord stimulation considered the next best option, surely a non-invasive, evidence based approach to transcutaneous neurostimulation should be offered first.</description>
		<content:encoded><![CDATA[<p>Hi Lorimer<br />
After reading your blog and comment re TENS and CRPS I wanted to respond as I have seen TENS like stimulation be affective when incorporated into the overall management plan for people with CRPS. Our company distributes the Interx device which we often descrive as &#8220;TENS&#8221; like, even though the application is very different.<br />
It may well be considered that TENS is not indicated for the treatment of pain relating to the condition CRPS due the lack of long term benefit or inconsistency of results that are commonly experienced. However, it may be necessary to look further into the way the technology is applied to determine whether or not it has a place in the treatment of such difficult conditions. TENS is a broad category which incorporates many different technologies applied in a variety of ways . The way a modality is used can have a significant affect on the outcomes achieved.</p>
<p>Recent analysis of the effect that treatment parameters of TENS have on pain relief clearly demonstrates that it is possible to optimize those parameters to achieve more pain relief.   The importance of treatment amplitude, pulse frequency and treatment location  have all been shown in recent literature and even in articles dated as far back as 1975 (Melzack et al)  .</p>
<p>Based upon my experience of the benefit of InterX therapy and the successful treatment of very difficult conditions including CRPS, Allodynia, Phantom Pain and others , I suggest that the technology of TENS which has barely evolved in the last 30 yrs limits the ability of a therapist to optimize treatment parameters for the effective relief of pain from CRPS. The protocols used with InterX dictate both an extra segmental and segmental approach for the treatment of CRPS. This includes contralateral treatment, treatment of the whole spine and the face and scalp. The crucial technological aspect of InterX is that it allows the identification of optimal treatment points within  chosen treatment areas while also delivering a significant dose of stimulation (typically 45mA). The identification of treatment points is based upon patients’ physiological response (increased sympathetic skin response) ,  and not arbitrary or anatomical points. The dose is an important factor and the InterX amplitude is approximately three times higher than Bjordal et al considered high amplitude and thus important for the success of a treatment.</p>
<p>If this scientific application of a modality excludes InterX from the classification of TENS then so be it, but it does not fall into the category of electroacupuncture either as points of low impedance are not always acupuncture points. As such InterX (Interactive Neurostimulation) may be considered in any of the above categories or in one of its own as a scientific delivery of high amplitude stimulation to points relating to a patients sympathetic nerve activity. Either way, it should be noted that even if  “TENS” is not indicated for the treatment of CRPS, it does not mean that TENS-like technologies when scientifically and correctly applied cannot offer sufferers of CRPS significant relief of their pain. This relief can bring them back into functional rehabilitation and ultimately to achieve long term relief with the aid of an integrated approach. With spinal cord stimulation considered the next best option, surely a non-invasive, evidence based approach to transcutaneous neurostimulation should be offered first.</p>
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		<title>By: Mark Brennan</title>
		<link>http://bodyinmind.com.au/what-is-complex-regional-pain-syndrome-in-plain-english/#comment-1509</link>
		<dc:creator>Mark Brennan</dc:creator>
		<pubDate>Tue, 22 Dec 2009 00:05:56 +0000</pubDate>
		<guid isPermaLink="false">http://www.bodyinmind.com.au/?p=2330#comment-1509</guid>
		<description>Cheers,  I have a guy at the mo who is awaiting nerve conduction tests to determine ulnar nerve function and although he does not fit the distinct criteria for CRPS I feel he is on a continuum.  Could there be elements of peripheral and central changes though therefore elements of type 1 and 2 and therefore graded Motor imagery and mirror box may help and could be part of overall management?. I feel its worth trying.</description>
		<content:encoded><![CDATA[<p>Cheers,  I have a guy at the mo who is awaiting nerve conduction tests to determine ulnar nerve function and although he does not fit the distinct criteria for CRPS I feel he is on a continuum.  Could there be elements of peripheral and central changes though therefore elements of type 1 and 2 and therefore graded Motor imagery and mirror box may help and could be part of overall management?. I feel its worth trying.</p>
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		<title>By: Lorimer</title>
		<link>http://bodyinmind.com.au/what-is-complex-regional-pain-syndrome-in-plain-english/#comment-1501</link>
		<dc:creator>Lorimer</dc:creator>
		<pubDate>Mon, 21 Dec 2009 05:05:39 +0000</pubDate>
		<guid isPermaLink="false">http://www.bodyinmind.com.au/?p=2330#comment-1501</guid>
		<description>We received this question via facebook: how do you feel about stellate ganglion blocks?  Here&#039;s a response to that question:

Check out this review: http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD004598/frame.html
This is what the &lt;a href=&quot;http://www.acc.co.nz/for-providers/clinical-best-practice/interventional-pain-management/interventions/intervention-index/WCM1_033973#P37_3501&quot; rel=&quot;nofollow&quot;&gt;New Zealand Accident Compensation Corporation&lt;/a&gt; 
says:
&quot;One guideline, three systematic reviews and one experimental study provided information on the effectiveness of sympathetic ganglion nerve block for complex regional pain syndrome (CRPS).

One high quality systematic review was identified evaluating the use of stellate and lumbar sympathetic ganglion blocks (Cepeda, 2002). It included 29 studies, three of which were randomised controlled trials. The majority of case series were retrospective and included small numbers of participants. The review included a meta-analysis of pain outcomes pooled from a sub-group of 14 studies in which the magnitude of treatment effects was quantified. Less than one third of people with CRPS (29%) obtained pain relief by three quarters of pre-treatment levels. The authors noted that the rate of success may be acceptable to many patients and practitioners but was consistent with a placebo response. Two other systematic reviews concluded that the limited amount and quality of the available evidence did not allow definite conclusions on the treatment’s effectiveness (Forounzanfar, 2002; Kingery, 1997). The guideline (Sanders, 1999) concluded that nerve blocking procedures should be limited to those patients in whom functional capacity can also be improved.

One randomised controlled trial was identified which was not included in the above Cepeda review (Tran, 2000). Seventeen people with CPRS I or II received a lumbar sympathetic nerve block using bupivacaine with iohexol (a contrast dye) or one using bupivacaine with saline. Both types of blocks resulted in significant pain relief from baseline to 1 hour post-block, and for six (iohexol / bupivacaine group) or three (saline / bupivacaine group) days afterwards.&quot;</description>
		<content:encoded><![CDATA[<p>We received this question via facebook: how do you feel about stellate ganglion blocks?  Here&#8217;s a response to that question:</p>
<p>Check out this review: <a target="_blank" href="http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD004598/frame.html"  rel="nofollow">http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD004598/frame.html</a><br />
This is what the <a target="_blank" href="http://www.acc.co.nz/for-providers/clinical-best-practice/interventional-pain-management/interventions/intervention-index/WCM1_033973#P37_3501"  rel="nofollow">New Zealand Accident Compensation Corporation</a><br />
says:<br />
&#8220;One guideline, three systematic reviews and one experimental study provided information on the effectiveness of sympathetic ganglion nerve block for complex regional pain syndrome (CRPS).</p>
<p>One high quality systematic review was identified evaluating the use of stellate and lumbar sympathetic ganglion blocks (Cepeda, 2002). It included 29 studies, three of which were randomised controlled trials. The majority of case series were retrospective and included small numbers of participants. The review included a meta-analysis of pain outcomes pooled from a sub-group of 14 studies in which the magnitude of treatment effects was quantified. Less than one third of people with CRPS (29%) obtained pain relief by three quarters of pre-treatment levels. The authors noted that the rate of success may be acceptable to many patients and practitioners but was consistent with a placebo response. Two other systematic reviews concluded that the limited amount and quality of the available evidence did not allow definite conclusions on the treatment’s effectiveness (Forounzanfar, 2002; Kingery, 1997). The guideline (Sanders, 1999) concluded that nerve blocking procedures should be limited to those patients in whom functional capacity can also be improved.</p>
<p>One randomised controlled trial was identified which was not included in the above Cepeda review (Tran, 2000). Seventeen people with CPRS I or II received a lumbar sympathetic nerve block using bupivacaine with iohexol (a contrast dye) or one using bupivacaine with saline. Both types of blocks resulted in significant pain relief from baseline to 1 hour post-block, and for six (iohexol / bupivacaine group) or three (saline / bupivacaine group) days afterwards.&#8221;</p>
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		<title>By: Lorimer</title>
		<link>http://bodyinmind.com.au/what-is-complex-regional-pain-syndrome-in-plain-english/#comment-1499</link>
		<dc:creator>Lorimer</dc:creator>
		<pubDate>Mon, 21 Dec 2009 01:59:33 +0000</pubDate>
		<guid isPermaLink="false">http://www.bodyinmind.com.au/?p=2330#comment-1499</guid>
		<description>yeah there is - as it was, type 2 if one can demonstrate a frank peripheral nerve lesion, type 1 if not. It is a bit dodgy though because whether one can or not depends on equipment and experience to some extent.  Still, i should change that - nice pick up.
L</description>
		<content:encoded><![CDATA[<p>yeah there is &#8211; as it was, type 2 if one can demonstrate a frank peripheral nerve lesion, type 1 if not. It is a bit dodgy though because whether one can or not depends on equipment and experience to some extent.  Still, i should change that &#8211; nice pick up.<br />
L</p>
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		<title>By: Mark Brennan</title>
		<link>http://bodyinmind.com.au/what-is-complex-regional-pain-syndrome-in-plain-english/#comment-1496</link>
		<dc:creator>Mark Brennan</dc:creator>
		<pubDate>Sun, 20 Dec 2009 16:57:12 +0000</pubDate>
		<guid isPermaLink="false">http://www.bodyinmind.com.au/?p=2330#comment-1496</guid>
		<description>Is there not a differentiation between type one and two anymore?</description>
		<content:encoded><![CDATA[<p>Is there not a differentiation between type one and two anymore?</p>
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